SERPINB3
SERPINB3

SERPINB3

2ZV6, 4ZK0, 4ZK36317n/aENSG00000057149n/aP29508n/aNM_006919n/aNP_008850n/aเซอร์ปิน บี3 (อังกฤษ: Serpin B3 หรือ SERPINB3, Squamous cell carcinoma antigen-1; SCCA1) เป็นโปรตีนของมนุษย์ และเป็นโปรตีนสมาชิกลำดับที่ 3 ในเคลดบีของมหาวงศ์เซอร์ปิน (Serpin family B member 3) ถูกถอดรหัสได้จากยีน SERPINB3 บนโครโมโซมคู่ที่ 18[3][4]

SERPINB3

Chr. Chromosome 18 (human)[1]
Available structuresPDBList of PDB id codes
Available structures
PDBHuman UniProt search: PDBe RCSB
List of PDB id codes

2ZV6, 4ZK0, 4ZK3

List of PDB id codes
List of PDB id codes

2ZV6, 4ZK0, 4ZK3

Location (UCSC) Chr 18: 63.66 – 63.66 Mb
UniProt

P29508

PubMed search [2]
RefSeq (protein)

NP_008850

Aliases SERPINB3, HsT1196, SCC, SCCA-1, SCCA-PD, SCCA1, T4-A, SSCA1, serpin family B member 3
RefSeq (mRNA)

NM_006919

PDB Human UniProt search: PDBe RCSB
Cellular component นิวเคลียสเซลล์
เวสิเคิล
cytoplasmic vesicle
เอกโซโซมชนิดภายนอกเซลล์
ไซโทพลาซึม
extracellular region
ภายนอกเซลล์
azurophil granule lumen
Gene ontologyMolecular functionCellular componentBiological process
Gene ontology
Molecular functionvirus receptor activity
protease binding
cysteine-type endopeptidase inhibitor activity
peptidase inhibitor activity
serine-type endopeptidase inhibitor activity
Cellular componentนิวเคลียสเซลล์
เวสิเคิล
cytoplasmic vesicle
เอกโซโซมชนิดภายนอกเซลล์
ไซโทพลาซึม
extracellular region
ภายนอกเซลล์
azurophil granule lumen
Biological processparacrine signaling
positive regulation of cell proliferation
autocrine signaling
GO:0048553 negative regulation of catalytic activity
negative regulation of JUN kinase activity
positive regulation of endopeptidase activity
positive regulation of epithelial to mesenchymal transition
negative regulation of proteolysis
negative regulation of endopeptidase activity
positive regulation of cell migration
viral entry
negative regulation of peptidase activity
neutrophil degranulation
Sources:Amigo / QuickGO
External IDs OMIM: 600517 HomoloGene: 130559 GeneCards: SERPINB3
End 63,661,893 bp[1]
Ensembl

ENSG00000057149

Molecular function virus receptor activity
protease binding
cysteine-type endopeptidase inhibitor activity
peptidase inhibitor activity
serine-type endopeptidase inhibitor activity
Species Human
Gene location (Human)Chr.BandStartEnd
Gene location (Human)
Chr.Chromosome 18 (human)[1]
Band18q21.33Start63,655,197 bp[1]
End63,661,893 bp[1]
BandStart 18q21.33
RNA expression pattern
RNA expression pattern




More reference expression data
Biological process paracrine signaling
positive regulation of cell proliferation
autocrine signaling
GO:0048553 negative regulation of catalytic activity
negative regulation of JUN kinase activity
positive regulation of endopeptidase activity
positive regulation of epithelial to mesenchymal transition
negative regulation of proteolysis
negative regulation of endopeptidase activity
positive regulation of cell migration
viral entry
negative regulation of peptidase activity
neutrophil degranulation
Entrez

6317