SERPINF2 Chr. Chromosome 17 (human)[1] Location (UCSC) Chr 17: 1.74 – 1.76 Mb UniProt P08697 List of PDB id codes List of PDB id codes2R9Y Available structuresPDBList of PDB id codes Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes2R9Y PubMed search [2] RefSeq (protein) NP_001159392 NP_001159393 XP_005256758 XP_016880254 NP_000925 NP_001159392 NP_001159393 XP_005256758 XP_016880254 Aliases SERPINF2, A2AP, AAP, ALPHA-2-PI, API, PLI, serpin family F member 2, alpha2AP RefSeq (mRNA) NM_001165920 NM_001165921 XM_005256701 XM_017024765 NM_000934 NM_001165920 NM_001165921 XM_005256701 XM_017024765 PDB Human UniProt search: PDBe RCSB Cellular component • blood microparticle• ไฟบริโนเจน• extracellular region• cell surface• เอกโซโซมชนิดภายนอกเซลล์• platelet alpha granule lumen• ภายนอกเซลล์• สารเคลือบเซลล์ที่มีคอลลาเจนเป็นส่วนประกอบ Gene ontologyMolecular functionCellular componentBiological process Gene ontologyMolecular function• peptidase inhibitor activity• protein homodimerization activity• protease binding• GO:0001948 การจับกับโปรตีน• serine-type endopeptidase inhibitor activity• endopeptidase inhibitor activityCellular component• blood microparticle• ไฟบริโนเจน• extracellular region• cell surface• เอกโซโซมชนิดภายนอกเซลล์• platelet alpha granule lumen• ภายนอกเซลล์• สารเคลือบเซลล์ที่มีคอลลาเจนเป็นส่วนประกอบBiological process• positive regulation of collagen biosynthetic process• negative regulation of peptidase activity• negative regulation of fibrinolysis• negative regulation of plasminogen activation• maintenance of blood vessel diameter homeostasis by renin-angiotensin• blood vessel morphogenesis• fibrinolysis• collagen fibril organization• platelet degranulation• positive regulation of JNK cascade• response to organic substance• acute-phase response• positive regulation of cell differentiation• positive regulation of ERK1 and ERK2 cascade• positive regulation of transforming growth factor beta production• positive regulation of stress fiber assembly• positive regulation of transcription by RNA polymerase II• positive regulation of smooth muscle cell proliferation• positive regulation of cell-cell adhesion mediated by cadherin• negative regulation of endopeptidase activitySources:Amigo / QuickGO External IDs OMIM: 613168 HomoloGene: 719 GeneCards: SERPINF2 End 1,755,265 bp[1] Ensembl ENSG00000167711ENSG00000276838 Molecular function • peptidase inhibitor activity• protein homodimerization activity• protease binding• GO:0001948 การจับกับโปรตีน• serine-type endopeptidase inhibitor activity• endopeptidase inhibitor activity RNA expression pattern RNA expression patternMore reference expression data Species Human Biological process • positive regulation of collagen biosynthetic process• negative regulation of peptidase activity• negative regulation of fibrinolysis• negative regulation of plasminogen activation• maintenance of blood vessel diameter homeostasis by renin-angiotensin• blood vessel morphogenesis• fibrinolysis• collagen fibril organization• platelet degranulation• positive regulation of JNK cascade• response to organic substance• acute-phase response• positive regulation of cell differentiation• positive regulation of ERK1 and ERK2 cascade• positive regulation of transforming growth factor beta production• positive regulation of stress fiber assembly• positive regulation of transcription by RNA polymerase II• positive regulation of smooth muscle cell proliferation• positive regulation of cell-cell adhesion mediated by cadherin• negative regulation of endopeptidase activity Gene location (Human)Chr.BandStartEnd Gene location (Human)Chr.Chromosome 17 (human)[1]Band17p13.3Start1,742,836 bp[1]End1,755,265 bp[1] BandStart 17p13.3 Entrez 5345