แอลฟาทู-แอนติพลาสมิโนเจน

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แอลฟาทู-แอนติพลาสมิโนเจน

Chr. Chromosome 17 (human)[1]
Available structuresPDBList of PDB id codes
Available structures
PDBHuman UniProt search: PDBe RCSB
List of PDB id codes

2R9Y

List of PDB id codes
List of PDB id codes

2R9Y

UniProt

P08697

Location (UCSC) Chr 17: 1.74 – 1.76 Mb
PubMed search [2]
RefSeq (protein)

NP_000925
NP_001159392
NP_001159393

Aliases SERPINF2, A2AP, AAP, ALPHA-2-PI, API, PLI, serpin family F member 2, alpha2AP
RefSeq (mRNA)

NM_000934
NM_001165920
NM_001165921

PDB Human UniProt search: PDBe RCSB
Gene ontologyMolecular functionCellular componentBiological process
Gene ontology
Molecular functionpeptidase inhibitor activity
protein homodimerization activity
protease binding
GO:0001948, GO:0016582 การจับกับโปรตีน
serine-type endopeptidase inhibitor activity
endopeptidase inhibitor activity
Cellular componentblood microparticle
ไฟบริโนเจน
extracellular region
cell surface
เอกโซโซมชนิดภายนอกเซลล์
platelet alpha granule lumen
ภายนอกเซลล์
สารเคลือบเซลล์ที่มีคอลลาเจนเป็นส่วนประกอบ
Biological processpositive regulation of collagen biosynthetic process
negative regulation of peptidase activity
negative regulation of fibrinolysis
negative regulation of plasminogen activation
maintenance of blood vessel diameter homeostasis by renin-angiotensin
blood vessel morphogenesis
fibrinolysis
collagen fibril organization
platelet degranulation
positive regulation of JNK cascade
response to organic substance
acute-phase response
positive regulation of cell differentiation
positive regulation of ERK1 and ERK2 cascade
positive regulation of transforming growth factor beta production
positive regulation of stress fiber assembly
GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
positive regulation of smooth muscle cell proliferation
positive regulation of cell-cell adhesion mediated by cadherin
negative regulation of endopeptidase activity
Sources:Amigo / QuickGO
Cellular component blood microparticle
ไฟบริโนเจน
extracellular region
cell surface
เอกโซโซมชนิดภายนอกเซลล์
platelet alpha granule lumen
ภายนอกเซลล์
สารเคลือบเซลล์ที่มีคอลลาเจนเป็นส่วนประกอบ
External IDs OMIM: 613168 HomoloGene: 719 GeneCards: SERPINF2
End 1,755,265 bp[1]
Ensembl

ENSG00000167711
ENSG00000276838

Molecular function peptidase inhibitor activity
protein homodimerization activity
protease binding
GO:0001948, GO:0016582 การจับกับโปรตีน
serine-type endopeptidase inhibitor activity
endopeptidase inhibitor activity
Gene location (Human)Chr.BandStartEnd
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17p13.3Start1,742,836 bp[1]
End1,755,265 bp[1]
BandStart 17p13.3
RNA expression pattern
RNA expression pattern
More reference expression data
Biological process positive regulation of collagen biosynthetic process
negative regulation of peptidase activity
negative regulation of fibrinolysis
negative regulation of plasminogen activation
maintenance of blood vessel diameter homeostasis by renin-angiotensin
blood vessel morphogenesis
fibrinolysis
collagen fibril organization
platelet degranulation
positive regulation of JNK cascade
response to organic substance
acute-phase response
positive regulation of cell differentiation
positive regulation of ERK1 and ERK2 cascade
positive regulation of transforming growth factor beta production
positive regulation of stress fiber assembly
GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
positive regulation of smooth muscle cell proliferation
positive regulation of cell-cell adhesion mediated by cadherin
negative regulation of endopeptidase activity
Species Human
Entrez

5345